# Fats and cardiovascular disease #
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## The best medicine against high blood pressure ##
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Fats and cardiovascular disease
The relationship between fat intake and the risk of cardiovascular disease (CVD) is a Central topic of modern nutritional medicine. Scientific studies show that not all fats are equal: their chemical structure and composition is influenced significantly by their effect on the human organism.
Types of fats and their properties
Fats can be divided into saturated, unsaturated, and TRANS-unsaturated fatty acids as described below:
Saturated fats are mainly in animal products such as Butter, Lard, and meat. A high intake of these fatty acids increases the levels of LDL cholesterol (bad cholesterol), which is associated with an increased risk for atherosclerosis and coronary heart disease.
Monounsaturated fatty acids (e.g. Oleic acid in olive oil) and polyunsaturated fatty acids (Omega‑3 and Omega‑6 fatty acids in fish, nuts, and seeds) are considered to be heart healthy. You can lower the LDL cholesterol and increase the HDL cholesterol (the good cholesterol).
TRANS fats are mainly caused by industrial hydrogenation of vegetable Oils (e.g., Margarine, Snacks, deep-Fried). They are considered to be particularly harmful, since they affect both the LDL and the HDL‑ cholesterol levels in a negative and inflammatory processes in the body to promote.
Mechanisms of the risk of emergence
Excessive consumption of saturated and TRANS unsaturated fatty acids promotes the development of atherosclerosis. This process begins with the deposition of LDL‑cholesterol in the vascular wall. This Plaques that narrow the vessel lumen and the blood flow velocity to reduce arise. In the long term, this can cause heart attacks, strokes, and peripheral arterial disease.
In addition, certain fats can trigger inflammatory reactions in the body. Chronic inflammation is considered to be an important risk factor for the development of cardiovascular diseases. TRANS fats and an Excess of Omega‑6 fatty acids (combined with a lack of Omega‑3 fatty acids) can enhance these processes.
Recommendations for fat intake
According to the recommendations of the world health organization (WHO) should fats account for 20-35% of daily energy intake. It should:
saturated fatty acids are limited to under 10% of the total energy;
TRANS fats, if possible, be avoided completely (target: under 1% of total energy);
unsaturated fatty acids are the main part of the fat intake, particularly Omega‑3 fatty acids from fish (two servings per week).
Conclusion
A balanced fat intake, with a focus on unsaturated fatty acids and the prevention of TRANS-fat is an important part of the prevention of cardiovascular diseases. The targeted modification of the diet can reduce the risk significantly, and for the improvement of cardiovascular health.
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Constant high levels of stress can disturb the blood flow and blood pressure and can damage vessels, and you may experience dizziness, extreme fatigue, or body aches with no wish to get out of bed. This stress-induced fatigue can make your blood pressure high and needs to be monitored. <a href="http://dientrotiendathc.com/media/ftp/urgent-diseases-of-the-circulatory-system.xml">http://dientrotiendathc.com/media/ftp/urgent-diseases-of-the-circulatory-system.xml</a>
## A medicine against high blood pressure lorista Losartan 5mg 12 ##
A medicine against high blood pressure: Lorista (Losartan) 5 mg
Introduction
High blood pressure (arterial hypertension) is one of the most common cardiovascular disease worldwide and a major risk factor for heart attacks, strokes and kidney disease. An effective pharmacological therapy is crucial for the prevention of these complications. An important drug in the treatment of hypertension is Lorista, whose active substance is Losartan.
Pharmacological classification and mechanism of action
Losartan belongs to the group of Angiotensin II receptor antagonists (AT₁ receptor blocker). The active ingredient in the binding of Angiotensin II binds to its receptors, in particular of the AT₁ receptors in blood vessels, heart, and kidney. This is achieved in the following:
Vasodilatation (enlargement of blood vessels);
Reduction of peripheral vascular resistance;
Reduction in Aldosterone secretion;
less Retention of sodium and water in the body;
protective effect on the heart and kidney.
Composition and dosage form
Lorista 5 mg is in the Form of tablets, with a plant-based casing covered. Each tablet contains:
Active ingredient: Losartan potassium 5 mg;
Auxiliary substances: lactose monohydrate, Microcrystalline cellulose, maize starch, povidone K30, Colloidal silicon dioxide, magnesium stearate, talc, Croscarmellose sodium (exact composition can vary from manufacturer to manufacturer).
Indications
The medical regulation in accordance with Lorista 5 mg is used in the following diseases:
Arterial hypertension as monotherapy or in combination with other antihypertensive agents.
Renal protection in patients with type 2 Diabetes mellitus and proteinuria to slowing the progression of kidney disease.
Reduction in the risk of stroke and heart attack in patients with hypertension and left ventricular hypertrophy.
Dosage and administration
The dosage is determined individually, and should always be done under medical supervision.
The standard dose for hypertension: 50 mg once daily. If necessary, the dose may be increased to 100 mg per day.
Starting dose (e.g. in the case of volumver reduction or concomitant intake of diuretics): 12.5 mg daily, gradually increased.
The tablet is swallowed whole, with or without food, at the same time of day taken.
Contraindications
Lorista should not be used in:
Pregnancy and breastfeeding (can cause damage to the fetus);
Age under 18 years (a lack of data on safety);
Hypersensitivity to Losartan or to any of the excipients;
severe liver disease;
Combination with Aliskiren in patients with diabetes;
hereditary intolerance of Lactose (if included).
Side effects
Possible side effects (depending on frequency):
Common: dizziness, fatigue, Hyperkalieämie (elevated potassium levels), gastrointestinal complaints (Nausea, diarrhea).
Uncommon: Headache, Sleep Disorders, Cough, Edema.
Rare: allergic reactions (urticaria, angioedema), renal dysfunction.
Upon the Occurrence of serious side effects, consult a physician.
Interactions with other drugs
Losartan may interact with other medicines inter:
Potassium-sparing diuretics, potassium supplements, increase the risk of a Hyperkalieämie.
NSAIDs (e.g., Ibuprofen): may diminish the antihypertensive effect and renal function compromise.
Other blood pressure lowering drugs: additive effect, possible hypotension.
Conclusion
Lorista (Losartan 5 mg) is a modern, effective and relatively safe drug for the treatment of hypertension and for the prevention of cardiovascular complications. The therapy should be individually tailored and under regular medical control. Before the beginning of the treatment, a careful medical history and, if necessary, laboratory tests (potassium, renal function) are required.
Note: This Text is for information purposes only and does not replace the medical advice. Before taking Lorista a doctor must be consulted.
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The drugs for the treatment of hypertension: An Overview of the most effective classes of substances
High blood pressure, also called hypertension, is one of the most common cardiovascular disease worldwide. According to estimates, billions of people suffer from this disease, which can result in untreated over the course of serious complications such as heart attack, stroke, or kidney failure be liable. Effective pharmacotherapy is therefore of crucial importance.
Goals of treatment
The primary goal in the treatment of arterial hypertension is to keep the blood pressure in the long term under 140/90 mmHg (or in the case of patients with an increased risk of 130/80 mmHg). This lowers the risk for cardiovascular events significantly. The choice of medication depends on the individual risk profile of the patient, the Presence of Comorbidities (e.g. Diabetes mellitus, chronic kidney disease) and possible side effects.
The Most Effective Groups Of Drugs
The current guideline recommends five main groups of antihypertensive drugs as first choice:
ACE inhibitors (Angiotensin‑converting enzyme inhibitor)
Examples: Enalapril, Ramipril.
Mechanism of action: inhibition of ACE, which leads to a decrease of Angiotensin II and thus a dilation of the blood vessels.
Particularly suitable for patients with Diabetes and proteinuria, since you have a renal protective effect.
AT1‑receptor blockers (Sartans)
Examples: Losartan, Valsartan.
Similar effect as ACE inhibitors, but with a lower frequency of cough as a side effect.
Calcium channel blockers
Examples: Amlodipine, Nifedipine.
Act through Blockade of calcium channels in smooth muscle cells of the vessels, which leads to vasodilation. Particularly effective in older patients and in isolated systolic hypertension.
Thiazide Diuretics
Example: Hydrochlorothiazide.
Lower blood pressure by reducing the fluid volume and peripheral vascular resistance. In a cost-effective and well studied, especially in combination therapies.
Beta-blockers
Examples: Metoprolol, Bisoprolol.
Originally as a standard therapy used, they are used today, especially in patients with heart failure or after myocardial infarction.
Combination therapy
Many patients will require to achieve the target blood pressure, a combination of at least two medications. Particularly effective combinations are:
ACE inhibitor + calcium channel blocker,
Sartan + Thiazide Diuretic.
These combinations show a synergistic effect and can reduce the Rate of side effects.
Conclusion
There is no best medication for all patients with hypertension. The individual therapy must be selected on the Basis of risk factors, Comorbidities, and impact. The five groups of Drugs, however, are to be regarded as scientifically sound and effective options. Early and consistent treatment can improve the food age, and the quality of life of the Affected significantly.
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## Research Institute for cardiovascular disease ##
Research Institute for cardiovascular disease: your Partner for health and progress
Cardiovascular diseases are a major cause of morbidity and mortality worldwide. We know that Every heart disease is individual and each solution is and must be.
In the research Institute for cardiovascular diseases, we combine excellence in research with a patient-oriented medicine. Our Team of leading cardiologists, molecular biologists, and Data scientists is working on ground-breaking methods for the prevention, diagnosis and treatment of heart and vascular diseases.
What we offer:
innovative research projects with a high level of clinical relevance;
Access to the latest diagnostic methods and technologies;
personalized treatment strategies based on genetic and biomarker-based analysis;
interdisciplinary cooperation with international research networks;
Education and prevention programs for the General population.
Our goal: The number of cardiovascular disorders in a sustained reduction — through Knowledge, Innovation and human proximity.
You can rely on Expertise that saves lives.
Contact us today to learn more about our research projects, prevention initiatives and possibilities for cooperation.
Research Institute for cardiovascular disease
Phone: 0800 8770120
E‑Mail:
Website: https://cardio.nashi-veshi.ru